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Bdrelin 3.75mg Injection

Original price was: ₹7,200.00.Current price is: ₹4,200.00.

  Prescription Required

Salt : Triptorelin

Manufacturer : Bdr Pharmaceuticals Internationals Pvt

Packing : 1 Vial in 1 Injection

Description

1. Product Introduction

Bdrelin 3.75mg Injection is a prescription medication that contains the active substance Triptorelin, a synthetic analogue of gonadotropin-releasing hormone (GnRH). It is a long-acting injectable formulation used to manage hormone-sensitive conditions by regulating the production of certain hormones in the body. Bdrelin works by initially stimulating and then significantly reducing the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn lowers sex hormone levels like testosterone and estrogen.

This medication is administered as an intramuscular injection under the supervision of a healthcare professional. It is particularly effective in treating hormone-dependent cancers and disorders like prostate cancer, endometriosis, uterine fibroids, and central precocious puberty (CPP).

2. Uses of This Medicine

Bdrelin 3.75mg Injection is used for the treatment of the following conditions:

  • Advanced Prostate Cancer: Triptorelin is used to reduce testosterone levels, which helps slow down the growth of prostate tumors that rely on this hormone.

  • Endometriosis: It helps relieve pelvic pain and reduce endometrial lesions by decreasing estrogen levels.

  • Uterine Fibroids: Used as pre-surgical treatment to reduce the size of fibroids and lessen bleeding.

  • Central Precocious Puberty (CPP): It delays early onset puberty in children by suppressing premature hormone production.

  • Assisted Reproductive Technology (ART): Triptorelin is sometimes used in fertility treatments to control the release of eggs and improve outcomes.

Always follow your doctor’s guidance and prescription for the right dosage and duration of treatment.

3. Benefits of This Medicine

  • Effective Hormone Suppression: Bdrelin provides controlled and sustained suppression of gonadal hormone production, which is crucial in managing hormone-sensitive diseases.

  • Tumor Shrinkage and Growth Control: In prostate cancer, it helps slow tumor growth and alleviate related symptoms such as bone pain and urinary difficulties.

  • Pain Relief in Endometriosis: By lowering estrogen, it helps reduce pelvic pain, menstrual cramps, and other symptoms related to endometriosis.

  • Delays Early Puberty: In children with CPP, it allows for more normal physical and emotional development by halting premature puberty.

  • Improved Surgical Outcomes: In uterine fibroids, shrinking the fibroids before surgery reduces blood loss and makes the operation easier.

  • Convenient Monthly Dosage: The once-a-month injection improves patient compliance and reduces the need for frequent hospital visits.

4. Side Effects

Like all medications, Bdrelin 3.75mg Injection may cause side effects in some individuals. While not everyone experiences them, it’s important to be aware of potential reactions:

Common Side Effects:

  • Hot flashes

  • Sweating

  • Headache

  • Mood changes (irritability, depression)

  • Decreased libido (sex drive)

  • Vaginal dryness or discomfort in women

  • Erectile dysfunction in men

  • Injection site pain or swelling

Less Common or Serious Side Effects:

  • Bone thinning (osteoporosis) with long-term use

  • Breast tenderness or enlargement

  • Weight gain

  • Muscle or joint pain

  • Menstrual irregularities or stoppage

  • Allergic reactions (rash, itching, swelling, breathing difficulty)

Contact your doctor if any side effects become severe or do not go away. Regular medical monitoring may be required during long-term therapy to assess bone density, hormone levels, or disease progression.

5. Frequently Asked Questions (FAQ)

Q1. How does Bdrelin 3.75mg Injection work?
Bdrelin contains Triptorelin, which suppresses the production of sex hormones by acting on the pituitary gland. This suppression helps manage conditions that are sensitive to estrogen or testosterone levels, such as prostate cancer and endometriosis.

Q2. How is this injection administered?
Bdrelin 3.75mg is given as an intramuscular injection, usually once every 28 days. A healthcare provider administers the dose under medical supervision.

Q3. How long does it take for Bdrelin to show results?
Initial hormonal flares may occur in the first few weeks, but effective suppression of hormones usually starts within 2–4 weeks. Full therapeutic benefits might take several weeks to months depending on the condition being treated.

Q4. Can Bdrelin cause an initial worsening of symptoms?
Yes. In men with prostate cancer, there may be a temporary increase in testosterone levels during the first week of treatment, which can temporarily worsen symptoms like bone pain or urinary problems. Doctors may prescribe additional medications to manage this effect.

Q5. Is Bdrelin safe during pregnancy or breastfeeding?
No, Bdrelin should not be used during pregnancy or breastfeeding. Women should use effective contraception during treatment and consult their doctor before planning a pregnancy.


References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1410-11.
  2. Triptorelin pamoate. Slough, Berkshire: Ipsen Ltd.; 2010 [revised 17 Dec. 2016]. [Accessed 23 Jan. 2019] (online) Avaialble from:External Link
  3. Triptorelin pamoate. Martigny, Switzerland: Debio RP; 2000 [Accessed Jul. 2014]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link


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