Bevacirel 100mg Injection

1. Product Introduction

Bevacirel 100mg Injection is a prescription medicine containing Bevacizumab, a recombinant humanized monoclonal antibody used primarily in cancer treatment. Bevacizumab is classified as a vascular endothelial growth factor (VEGF) inhibitor, which works by inhibiting the formation of new blood vessels (angiogenesis) that tumors need to grow and spread. By blocking VEGF, Bevacizumab starves the tumor of its blood supply, thus slowing or stopping its growth.

Bevacirel 100mg is administered intravenously by a healthcare professional in a clinical setting. It is used either alone or in combination with chemotherapy to treat several types of cancer, including colorectal cancer, lung cancer, kidney cancer, ovarian cancer, and glioblastoma.

This medicine is a vital part of targeted cancer therapy, and its role is particularly important in advanced or metastatic cancers. It is well-researched, widely used, and recommended in various national and international treatment guidelines.

2. Uses of Bevacirel 100mg Injection

Bevacirel 100mg is used in the treatment of various cancers, particularly those that are advanced or have metastasized. Common indications include:

• Metastatic Colorectal Cancer (mCRC):
  Used in combination with chemotherapy (like 5-FU-based regimens) to improve progression-free survival.

• Non-Small Cell Lung Cancer (NSCLC):
  Often combined with platinum-based chemotherapy to treat advanced or recurrent disease.

• Renal Cell Carcinoma (Kidney Cancer):
  Used in combination with interferon alfa for advanced kidney cancer.

• Cervical Cancer and Ovarian Cancer:
  Especially in persistent, recurrent, or metastatic cases when combined with chemotherapy.

• Glioblastoma Multiforme (Brain Cancer):
  Approved for use in recurrent glioblastoma where other treatments have failed.

• Hepatocellular Carcinoma (Liver Cancer):
  In combination with other agents as part of first-line treatment in unresectable cases.

• Breast Cancer (off-label in some regions):
  Though not universally approved, it is sometimes used in triple-negative breast cancer as part of individualized treatment plans.

3. Benefits of Bevacirel 100mg Injection

• Targeted Therapy:
  Unlike traditional chemotherapy that affects both cancerous and healthy cells, Bevacirel specifically targets blood vessels feeding the tumor, making it more selective and effective.

• Improves Survival:
  When used with chemotherapy, Bevacizumab has shown significant improvements in overall survival and progression-free survival in various cancers.

• Reduces Tumor Growth and Spread:
  By inhibiting angiogenesis, the medication limits the tumor’s ability to grow and metastasize.

• Versatile Cancer Treatment:
  Effective in treating a wide range of solid tumors, especially advanced and metastatic cancers.

• Enhances Chemotherapy:
  Bevacirel boosts the effectiveness of chemotherapy agents by normalizing blood vessels in tumors, improving drug delivery.

4. Side Effects

Like all powerful anti-cancer agents, Bevacirel 100mg Injection may cause some side effects. Most are manageable under medical supervision, but it’s important for patients to report any unusual symptoms.

Common Side Effects:

• High blood pressure (hypertension)

• Fatigue or weakness

• Nosebleeds

• Diarrhea

• Loss of appetite

• Mouth sores

• Delayed wound healing

• Protein in the urine

Serious Side Effects (Less Common):

• Gastrointestinal perforation (tear in the stomach or intestines)

• Blood clots (stroke or heart attack)

• Severe bleeding

• Kidney problems (including nephrotic syndrome)

• Infusion-related reactions (fever, chills, difficulty breathing)

Precautions:

• Avoid during pregnancy; it may harm the unborn baby.

• Patients undergoing surgery should delay Bevacizumab due to the risk of poor wound healing.

• Regular monitoring of blood pressure, urine protein levels, and renal function is advised.

5. Frequently Asked Questions (FAQ)

Q1. What is Bevacirel 100mg Injection used for?
A: It is used for treating various types of advanced or metastatic cancers, such as colorectal, lung, kidney, brain, ovarian, and cervical cancers.

Q2. How does Bevacizumab work?
A: Bevacizumab blocks a protein called VEGF that promotes the growth of blood vessels in tumors. By inhibiting this protein, it cuts off the blood supply to cancer cells, thereby stopping tumor growth.

Q3. How is this injection given?
A: Bevacirel is given as an intravenous (IV) infusion under the supervision of a trained healthcare professional. The infusion typically takes between 30 to 90 minutes.

Q4. Is Bevacirel chemotherapy?
A: No, it is not traditional chemotherapy. It is a targeted monoclonal antibody therapy, often used in combination with chemotherapy.

Q5. Can Bevacirel cure cancer?
A: Bevacirel does not cure cancer but helps in slowing down tumor progression, improving quality of life, and extending survival in patients with advanced cancer.