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Cresp 40 Injection

Original price was: ₹3,019.50.Current price is: ₹1,150.00.

 Prescription Required

 Cold chain

Salt : Darbepoetin alfa (40mcg)

Manufacturer : Dr Reddy’S Laboratories Ltd

Packing : 0.4 ml in 1 prefilled syringe

Prepaid Only, Non-Returnab

Description

Product Introduction

Cresp 40 Injection is a prescription medicine that contains Darbepoetin alfa, a synthetic form of erythropoietin, which is a hormone naturally produced by the kidneys to stimulate red blood cell production. It is primarily used to treat anemia caused by chronic kidney disease (CKD) or chemotherapy in cancer patients. By increasing red blood cell (RBC) production, Cresp 40 helps improve oxygen delivery in the body, reducing symptoms like fatigue, weakness, and shortness of breath associated with anemia.

Manufactured with advanced biotechnology, Cresp 40 Injection is designed for subcutaneous (under the skin) or intravenous (into a vein) administration under the supervision of a healthcare professional. It is important to follow your doctor’s dosage instructions and regularly monitor your hemoglobin levels while on this therapy.


Uses of Cresp 40 Injection

Cresp 40 Injection is indicated for the treatment of anemia associated with:

  • Chronic Kidney Disease (CKD) in adults and children, including patients on dialysis and not on dialysis.
  • Chemotherapy-induced anemia in patients undergoing chemotherapy for certain types of cancers such as non-myeloid malignancies.
  • Anemia in HIV-infected patients treated with zidovudine (in certain cases).
  • Anemia before surgery to reduce the need for blood transfusion, especially in cases where patients are expected to have significant blood loss.

Cresp 40 helps to reduce the need for red blood cell transfusions by promoting the body’s natural production of RBCs.


Benefits of Cresp 40 Injection

âś… 1. Effective Treatment for Anemia

Cresp 40 Injection effectively stimulates bone marrow to produce red blood cells, helping to correct anemia and improve hemoglobin levels.

âś… 2. Reduces Dependence on Blood Transfusions

By enhancing RBC production, it significantly reduces or eliminates the need for frequent blood transfusions, minimizing associated risks like infections or iron overload.

âś… 3. Improves Quality of Life

Patients suffering from anemia often experience chronic fatigue, weakness, and reduced physical performance. Cresp 40 helps restore energy levels and overall vitality, enabling better daily functioning.

âś… 4. Convenient Dosage Regimen

Depending on the severity of anemia and patient’s response, Cresp 40 can be administered once weekly, biweekly, or monthly, offering flexibility and ease of use.

âś… 5. Essential for Chemotherapy Patients

In cancer patients receiving chemotherapy, Cresp 40 Injection helps counteract anemia caused by chemotherapy drugs, allowing them to continue their treatment without severe side effects of anemia.

âś… 6. Improves Outcomes in CKD

In patients with chronic kidney disease, maintaining appropriate hemoglobin levels with Cresp 40 can prevent cardiovascular complications, improving overall prognosis and survival.


Side Effects of Cresp 40 Injection

Like all medications, Cresp 40 Injection may cause side effects, although not everyone gets them. The most commonly reported side effects include:

  • Hypertension (high blood pressure)
  • Headache
  • Body pain and muscle aches
  • Injection site reactions (redness, swelling, pain)
  • Fever
  • Nausea or vomiting
  • Diarrhea or constipation
  • Fatigue or dizziness

⚠️ Serious but Rare Side Effects:

  • Blood clots (deep vein thrombosis, pulmonary embolism)
  • Stroke or heart attack (especially if hemoglobin levels are too high)
  • Seizures (rare)
  • Pure red cell aplasia (PRCA) (a condition where the body stops producing red blood cells)

If you experience chest pain, shortness of breath, swelling in legs, severe headache, vision changes, or signs of an allergic reaction (rash, itching, swelling, severe dizziness, trouble breathing), seek immediate medical attention.


Frequently Asked Questions (FAQ)

1. What is Cresp 40 Injection used for?

Cresp 40 is primarily used to treat anemia caused by chronic kidney disease and chemotherapy. It helps the body make more red blood cells, improving symptoms like fatigue and weakness.

2. How is Cresp 40 Injection administered?

Cresp 40 is given either subcutaneously (under the skin) or intravenously (into a vein), usually by a healthcare professional. The dosage and frequency depend on your medical condition, hemoglobin level, and response to therapy.

3. How long does it take for Cresp 40 to work?

You may start to notice an improvement in symptoms such as energy levels and reduced fatigue within a few weeks of starting Cresp 40. However, it may take longer for hemoglobin levels to stabilize, depending on the severity of anemia.

4. Can Cresp 40 be self-administered?

In some cases, if advised by your doctor, trained patients or caregivers can administer Cresp 40 Injection at home. Proper technique and dosage instructions must be followed carefully. Never attempt to inject without medical guidance.

5. Is it safe to use Cresp 40 Injection during pregnancy or breastfeeding?

There is limited data on the use of Darbepoetin alfa during pregnancy or breastfeeding. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this medication.


References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
  3. Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  4. Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. [Accessed 07 Apr. 2019] (online) Available from:External Link
  5. CiplaMed. Darbepoetin Alfa [Product Information]. [Last Reviewed: June 2019]. [Accessed 17 Jun. 2023] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Darbepoetin. [Accessed 17 Jun. 2023] (online) Available from:External Link
  7. Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019. [Accessed 17 Jun. 2023] (online) Available from:External Link
  8. Aranesp Injection (Darbepoetin alfa) [Product Information]. [Accessed 17 Jun. 2023] (online) Available from:External Link

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Shipping & Delivery

Shipping Policy

We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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