Eltoplate 50mg Tablet

1. Product Introduction

Eltoplate 50mg Tablet is an oral medication that contains Eltrombopag, a thrombopoietin receptor agonist. It is used to increase platelet production in patients who have low platelet counts due to certain medical conditions, including chronic immune thrombocytopenic purpura (ITP), hepatitis C-associated thrombocytopenia, and severe aplastic anemia.

Eltrombopag works by stimulating the thrombopoietin receptors on bone marrow cells, thereby encouraging the production of platelets. Unlike corticosteroids or immunoglobulin therapies that suppress the immune system, Eltrombopag directly promotes the body’s natural platelet generation process. It is especially useful in patients who have not responded adequately to other treatments or need long-term platelet support.

Eltoplate 50mg Tablet is typically prescribed by a specialist and should be taken exactly as directed. It may be used alone or in combination with other medications depending on the patient’s condition.

2. Uses of This Medicine

Eltoplate 50mg Tablet is primarily used to treat:

• Chronic Immune Thrombocytopenic Purpura (ITP): A condition where the immune system destroys platelets, increasing the risk of bruising and bleeding. Eltrombopag is used when other treatments like steroids or immunoglobulins have failed.

• Thrombocytopenia in Hepatitis C: Used in patients with chronic hepatitis C to manage low platelet counts and allow initiation or continuation of interferon-based treatment.

• Severe Aplastic Anemia (SAA): In combination with other treatments or alone in patients who have had an insufficient response to immunosuppressive therapy.

3. Benefits of This Medicine

• Effective Platelet Boost: Eltrombopag increases platelet production in the bone marrow, helping to maintain a stable count.

• Reduced Bleeding Risk: With higher platelet levels, patients experience fewer bleeding episodes and a lower risk of spontaneous hemorrhage.

• Alternative to Invasive Therapies: Especially helpful for patients who are not candidates for splenectomy or cannot tolerate corticosteroids.

• Support for Antiviral Therapy: In hepatitis C patients, it allows continuation of antiviral therapy by improving platelet count.

• Improved Quality of Life: Patients often report fewer hospital visits, less need for transfusions, and greater peace of mind.

4. Side Effects

As with any medication, Eltoplate 50mg Tablet may cause side effects. While many are mild and temporary, some can be serious and require medical attention.

Common Side Effects:

• Headache

• Nausea

• Diarrhea

• Fatigue

• Upper respiratory tract infections

• Muscle or joint pain

Less Common/Serious Side Effects:

• Liver problems: Elevation in liver enzymes and bilirubin. Routine liver function tests are recommended.

• Thromboembolism: Increased platelet count can lead to the formation of blood clots, especially if not closely monitored.

• Cataracts: In rare cases, cataract development has been observed.

• Bone marrow changes: Long-term use may affect the bone marrow structure.

Patients should report any unusual bruising, yellowing of the skin or eyes, dark urine, vision changes, or signs of a blood clot (chest pain, shortness of breath, swelling in limbs) to their healthcare provider promptly.

5. Frequently Asked Questions (FAQ)

Q1. How should I take Eltoplate 50mg Tablet?

Take this medicine on an empty stomach, at least 1 hour before or 2 hours after a meal. Avoid taking it with dairy products, antacids, or supplements containing iron, calcium, or magnesium, as they can reduce its effectiveness.

Q2. How long does it take for Eltoplate to work?

Most patients begin to notice an improvement in platelet count within 1 to 2 weeks, though it may vary depending on the condition being treated.

Q3. Can I stop taking Eltoplate if I feel better?

No, do not stop taking this medicine without consulting your doctor. Stopping suddenly can cause platelet counts to fall dangerously low.

Q4. Is Eltoplate safe during pregnancy or breastfeeding?

The safety of Eltrombopag during pregnancy and breastfeeding is not well established. It should only be used if clearly necessary and under medical supervision.

Q5. Are there dietary restrictions while on this medication?

Yes. Avoid taking the tablet with food, especially calcium-rich foods, as they interfere with absorption. Your doctor may provide a specific dietary schedule.