Encicarb 500 Injection

1. Product Introduction

Encicarb 500 Injection is an intravenous iron formulation that contains Ferric Carboxymaltose (500mg). It is used to treat iron deficiency anemia (IDA) in patients who are either intolerant to oral iron supplements or require rapid replenishment of iron stores due to significant deficiencies. Unlike traditional oral iron therapy, Encicarb provides a quick and effective solution for restoring iron levels in the body, especially in cases where oral administration is not feasible.

This injection is administered by a healthcare professional, usually in a hospital or clinical setting. Its high iron content and controlled release profile allow for larger doses to be administered in a single sitting, reducing the number of required treatments and improving patient compliance.

Encicarb is a preferred choice for treating anemia in patients with chronic kidney disease, inflammatory bowel disease, or heavy uterine bleeding, as well as during pregnancy under medical supervision.

2. Uses of This Medicine

Encicarb 500 Injection is primarily indicated for the treatment of iron deficiency anemia in the following situations:

• Chronic Kidney Disease (CKD) – Patients undergoing dialysis or not on dialysis but have poor absorption or intolerance to oral iron.

• Postpartum Anemia – Following significant blood loss after childbirth.

• Heavy Menstrual Bleeding (Menorrhagia) – When oral iron isn’t sufficient to replenish the iron lost.

• Inflammatory Bowel Disease (IBD) – Such as Crohn’s disease or ulcerative colitis, where oral iron may aggravate symptoms.

• Cancer-related Anemia – In patients with malignancies, particularly when receiving chemotherapy.

• Postoperative or Perioperative Anemia – To manage blood loss during or after surgery.

• Intolerance to Oral Iron Supplements – Patients experiencing gastrointestinal side effects like nausea, vomiting, or constipation.

3. Benefits of This Medicine

Encicarb 500 Injection offers several key benefits over traditional oral iron supplements and other injectable formulations:

✓ Rapid Iron Replenishment

Ferric carboxymaltose allows for high doses (up to 1000 mg) to be administered at once, replenishing iron stores more quickly than oral iron.

✓ Improved Patient Compliance

Fewer doses mean fewer clinic visits and better adherence to treatment plans.

✓ Reduced Gastrointestinal Side Effects

Unlike oral iron tablets, Encicarb bypasses the gastrointestinal tract, thus avoiding common side effects like constipation, nausea, and abdominal discomfort.

✓ Suitable for Special Populations

Particularly useful in patients with chronic illnesses (CKD, IBD, cancer) where oral iron may not be effective.

✓ Safe in Pregnancy (Under Medical Supervision)

Encicarb can be used during the second and third trimesters of pregnancy when required and prescribed by a doctor.

✓ Sustained Iron Release

Its controlled release mechanism ensures that iron is gradually made available in the body, reducing oxidative stress and tissue damage.

4. Side Effects

While Encicarb 500 Injection is generally well tolerated, like all medications, it can cause side effects in some patients.

Common Side Effects:

• Headache

• Dizziness or light-headedness

• Nausea

• Injection site pain or swelling

• Metallic taste in the mouth

• Flushing or warmth sensation

Uncommon or Rare Side Effects:

• Low blood pressure (hypotension) during infusion

• Muscle cramps or joint pain

• Skin rash or itching

• Increased liver enzymes (rarely)

• Allergic or hypersensitivity reactions (extremely rare)

Serious Reactions:

• Anaphylaxis (very rare but life-threatening): Symptoms include chest tightness, shortness of breath, and swelling of the face or throat. This requires immediate medical attention.

It is essential to monitor the patient during and after infusion for any signs of adverse reactions. Always inform the healthcare provider about any past allergic reactions to injectable iron products.

5. Frequently Asked Questions (FAQ)

Q1. What is Encicarb 500 Injection used for?
Encicarb is used to treat iron deficiency anemia, especially in people who cannot tolerate oral iron or need quick replenishment of iron.

Q2. How is this medicine administered?
It is given as an intravenous (IV) infusion or slow injection by a trained healthcare professional.

Q3. How many doses are needed?
Depending on the severity of anemia and the patient’s weight, a total dose can often be delivered in one or two sittings. Your doctor will determine the appropriate dosing schedule.

Q4. Is Encicarb safe during pregnancy?
Yes, it can be used during the second and third trimesters of pregnancy under a doctor’s supervision when oral iron is ineffective or not tolerated.

Q5. Can I take this medicine if I have liver disease?
Caution is advised. Liver function should be monitored, and the doctor will evaluate whether it’s safe to use in such cases.