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Geftinat 250mg Tablet

Original price was: ₹5,900.00.Current price is: ₹2,800.00.

  Prescription Required

Salt : Gefitinib

Manufacturer : NATCO PHARMA LTD

Packing : 30 Tablet(S) In A Strip

Description

1. Product Introduction

Geftinat 250mg Tablet is a targeted cancer therapy medicine that contains the active ingredient Gefitinib, a tyrosine kinase inhibitor (TKI). This medicine is primarily used in the treatment of non-small cell lung cancer (NSCLC), especially in patients whose cancer is driven by mutations in the epidermal growth factor receptor (EGFR) gene.

Gefitinib works by specifically blocking the signals that tell cancer cells to grow. Unlike conventional chemotherapy, Geftinat targets only the cancerous cells, minimizing damage to normal healthy cells. It is prescribed for patients who have locally advanced or metastatic NSCLC and have not responded well to prior chemotherapy.

Geftinat is taken orally and offers a convenient at-home treatment option for patients, making it a preferred choice in many treatment protocols.


2. Uses of This Medicine

Geftinat 250mg Tablet is prescribed for:

  • Non-Small Cell Lung Cancer (NSCLC):
    Used as a first-line treatment in patients with EGFR mutation-positive advanced or metastatic NSCLC.

  • Recurrent or Progressive Lung Cancer:
    Often given to patients whose cancer has returned or continued to grow after chemotherapy or radiation.

  • Maintenance Therapy:
    In some cases, it is used as ongoing treatment to prevent the cancer from coming back after initial response.

Note: Before initiating Gefitinib therapy, genetic testing is recommended to confirm the presence of EGFR mutations, as this drug is effective mainly in EGFR-mutant tumors.


3. Benefits of This Medicine

Geftinat 250mg Tablet offers several key benefits for lung cancer patients:

  • Targeted Therapy:
    Gefitinib selectively inhibits the EGFR protein, which is overactive in certain lung cancers. This precision reduces harm to normal cells and improves outcomes.

  • Improved Progression-Free Survival:
    Clinical studies have shown that Gefitinib delays cancer progression more effectively than standard chemotherapy in EGFR-mutated NSCLC patients.

  • Better Tolerability:
    Compared to chemotherapy, Geftinat causes fewer side effects such as hair loss, nausea, and immune suppression.

  • Oral Administration:
    The tablet form allows for easier administration and eliminates the need for hospital-based infusions.

  • Improved Quality of Life:
    Patients experience relief from lung cancer symptoms like breathlessness, persistent cough, and fatigue, allowing them to resume daily activities.

  • Alternative for Elderly or Unfit Patients:
    Suitable for patients who may not tolerate traditional chemotherapy well due to age or comorbidities.


4. Side Effects

While Geftinat is generally better tolerated than traditional chemotherapy, it may still cause some side effects. Most are manageable and diminish over time or with supportive care.

Common Side Effects:

  • Diarrhea

  • Skin rash or acne

  • Dry skin

  • Nausea

  • Loss of appetite

  • Fatigue

  • Itching

  • Eye irritation or dry eyes

Serious Side Effects (Seek Immediate Medical Attention):

  • Breathing difficulty or cough (may indicate interstitial lung disease)

  • Severe diarrhea or dehydration

  • Liver function abnormalities

  • Blistering or peeling skin

  • Vision changes

Tip: Regular blood tests and monitoring are essential during treatment to manage side effects early and adjust dosage if needed.


5. Frequently Asked Questions (FAQ)

Q1. What is Geftinat 250mg Tablet used for?
A: Geftinat is primarily used to treat non-small cell lung cancer (NSCLC) that has EGFR gene mutations. It helps stop or slow the growth of cancer cells.

Q2. How does Gefitinib work?
A: Gefitinib blocks the action of EGFR (a protein that helps cancer cells grow and divide). By inhibiting this protein, the medicine prevents tumor growth and spread.

Q3. How should I take Geftinat?
A: Take one tablet (250mg) once daily, at the same time each day, with or without food. Swallow whole with water. Do not crush or chew.

Q4. What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember on the same day. Do not take two doses the next day to make up for it.

Q5. Can women take Geftinat?
A: Yes, Geftinat can be prescribed to both men and women. However, women of childbearing age should avoid becoming pregnant while on this medicine.


References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1734-35.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 616-17.
  4. Gefitinib. Luton, Bedfordshire: AstraZeneca UK Limited; 2009 [revised 23 Apr. 2018]. [Accessed 232 Jan. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Gefitinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  7. CiplaMed. Gefitinib [Prescribing Information]. [Accessed 06 Apr. 2024] (online) Available from: External Link


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Shipping & Delivery

Shipping Policy

We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

Delivery

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Your purchases may reach you from various locations in more than one package. But rest assured, you will be charged one delivery fee for the entire order. As soon as your package ships, we will email you your package tracking information.

We are bound in coverage by their reach even though we use some of India’s largest logistics companies for shipping. In case your address is in a location not served by them we would contact you to find an alternative solution to make your products reach you.