Hemazide O 200mg Tablet

1. Product Introduction

Hemazide O 200mg Tablet is an oral anticancer medication that contains Azacitidine (200mg) as its active ingredient. Azacitidine belongs to a class of drugs known as hypomethylating agents and is used in the treatment of certain types of blood and bone marrow cancers, particularly myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).

Hemazide O works by altering the way cancer cells grow and divide. It incorporates into the DNA and RNA of cancer cells, inhibiting abnormal cell division and restoring normal cell function. The oral formulation offers greater convenience compared to traditional injectable treatments, allowing patients to receive therapy at home under medical supervision.

This medicine is an essential part of chemotherapy regimens for patients with high-risk blood cancers who may not be candidates for intensive chemotherapy or stem cell transplantation.

2. Uses of This Medicine

Hemazide O 200mg Tablet is used primarily for the treatment of:

• Myelodysplastic Syndromes (MDS): A group of disorders where the bone marrow fails to produce healthy blood cells.

• Acute Myeloid Leukemia (AML): A fast-growing cancer of the blood and bone marrow, particularly in elderly or unfit patients.

• Chronic Myelomonocytic Leukemia (CMML): A type of cancer that has features of both MDS and myeloproliferative disorders.

It is especially effective in patients who are not eligible for more aggressive treatments like bone marrow transplantation.

3. Benefits of This Medicine

Hemazide O 200mg offers several important benefits in cancer treatment:

• Oral Convenience: Unlike conventional Azacitidine injections, this tablet form is taken orally, allowing for greater ease of administration and patient comfort.

• Slows Disease Progression: It helps to delay or stop the advancement of MDS and AML, increasing the duration of remission and reducing complications.

• Improves Blood Counts: By restoring bone marrow function, it helps increase the number of red blood cells, white blood cells, and platelets.

• Reduces Transfusion Needs: Many patients experience a reduced dependency on blood transfusions after treatment.

• Extends Survival: Clinical studies have shown that Azacitidine extends overall survival in patients with high-risk MDS and elderly AML.

• Tolerable Side Effect Profile: When compared to more intensive chemotherapy, Azacitidine is generally better tolerated, especially in older adults.

4. Side Effects

While Hemazide O 200mg is generally well-tolerated, it may cause side effects in some patients. Monitoring and early management can help reduce their severity.

Common Side Effects:

• Nausea and vomiting

• Diarrhea or constipation

• Fatigue or weakness

• Loss of appetite

• Low blood cell counts (anemia, neutropenia, thrombocytopenia)

• Injection-site reactions (if used in injectable form)

Serious Side Effects:

• Infections due to low white blood cells (fever, chills)

• Bleeding or bruising due to low platelet count

• Liver function abnormalities

• Kidney problems

• Shortness of breath or chest discomfort

Precautions:

• Regular blood tests are essential to monitor blood cell counts and liver/kidney function.

• Patients should report any signs of infection, bleeding, or unusual fatigue to their doctor.

• Women of childbearing age should use effective contraception during treatment.

If any side effect becomes severe or persistent, consult your doctor immediately.

5. Frequently Asked Questions (FAQ)

Q1. What is Hemazide O 200mg Tablet used for?
A: Hemazide O is used for treating myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), and chronic myelomonocytic leukemia (CMML), especially in patients who are not fit for intensive chemotherapy.

Q2. How does Azacitidine in Hemazide O work?
A: Azacitidine works by interfering with DNA and RNA synthesis in abnormal cells, slowing down or stopping their growth and helping the bone marrow produce healthy blood cells.

Q3. How should I take Hemazide O 200mg Tablet?
A: Take the tablet exactly as prescribed by your doctor. It is usually taken once daily for a specific number of days in a treatment cycle. Swallow it with water and do not crush or chew.

Q4. Can I take Hemazide O at home?
A: Yes, one of the main advantages of this oral tablet is that it can be taken at home. However, regular blood monitoring and medical follow-up are essential.

Q5. What happens if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double the dose to catch up.