

Letroz 2.5mg Tablet 30’s
₹878.00 Original price was: ₹878.00.₹680.00Current price is: ₹680.00.
Prescription Required
Salt : Letrozole (2.5mg)
Manufacturer : SUN PHARMA
Packing : 10 capsules in 1 strip
1. Product Introduction
Letroz 2.5mg Tablet is a prescription medication containing Letrozole, a drug that belongs to the class of aromatase inhibitors. It is widely used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. The medicine works by lowering the estrogen levels in the body, which helps slow or reverse the growth of estrogen-dependent breast tumors.
Letrozole is often prescribed as adjuvant therapy (treatment after surgery) or as first-line therapy for advanced or metastatic breast cancer. It may also be used as a fertility treatment in certain cases for women with ovulation issues, although this is considered an off-label use.
Letroz 2.5mg Tablet should be taken orally with or without food, usually once daily, or as directed by the healthcare provider. Consistent dosing is essential for optimal results, and regular monitoring is often required to assess treatment effectiveness and manage any side effects.
2. Uses of Letroz 2.5mg Tablet
Letroz 2.5mg Tablet is primarily used in the following conditions:
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Breast Cancer in Postmenopausal Women:
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Early-stage hormone receptor-positive breast cancer (after surgery, chemotherapy, or radiation)
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Advanced or metastatic breast cancer that has spread beyond the breast and lymph nodes
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Prevention of cancer recurrence in high-risk patients
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Off-label Use:
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Ovulation Induction in Women with PCOS (Polycystic Ovary Syndrome) or infertility – under medical supervision
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3. Benefits of Letroz 2.5mg Tablet
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Effective in Hormone-Sensitive Breast Cancer: Letrozole significantly reduces estrogen levels, which helps to stop or slow the growth of breast cancer cells that rely on estrogen.
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Improves Survival Rates: Clinical studies have shown that Letrozole can increase disease-free survival and reduce the risk of recurrence in postmenopausal women with hormone-positive breast cancer.
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Convenient Oral Therapy: Unlike chemotherapy or injectable treatments, Letroz 2.5mg comes in tablet form, making it convenient for long-term use at home.
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Post-Surgery Maintenance: Often used as a maintenance therapy following surgery, chemotherapy, or radiation to prevent cancer recurrence.
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Alternative for Tamoxifen: For postmenopausal women, Letrozole is considered a strong alternative or follow-up treatment after tamoxifen therapy.
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Support for Fertility in Special Cases: In women struggling with ovulation, Letrozole may be prescribed (off-label) to stimulate ovulation due to its effect on hormonal balance.
4. Side Effects
Like all medications, Letroz 2.5mg Tablet may cause side effects, though not everyone experiences them. Most side effects are mild and manageable, but some may require medical attention.
Common Side Effects:
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Hot flashes
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Fatigue or weakness
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Headache
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Joint or muscle pain (arthralgia/myalgia)
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Dizziness
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Increased sweating
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Nausea
Less Common but Serious Side Effects:
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Osteoporosis or reduced bone mineral density
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High cholesterol levels
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Mood swings or depression
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Vaginal dryness or discomfort
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Elevated liver enzymes
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Increased risk of cardiovascular events in susceptible individuals
Important Note: Long-term use may lead to bone thinning, so periodic bone density tests and calcium/vitamin D supplementation are often recommended.
5. Frequently Asked Questions (FAQ)
Q1. How does Letroz 2.5mg Tablet work?
A: Letrozole blocks the enzyme aromatase, which is responsible for converting androgens into estrogens. By lowering estrogen levels in the body, it slows the growth of hormone receptor-positive breast tumors.
Q2. Can Letroz be used for fertility treatment?
A: Yes, Letrozole is sometimes used off-label to induce ovulation in women with infertility or PCOS. However, this use should only be under the supervision of a fertility specialist.
Q3. How long should I take Letroz 2.5mg Tablet for breast cancer?
A: Duration depends on your treatment plan. It is typically taken for 5 years but may be extended to 7–10 years in some high-risk patients. Always follow your doctor’s instructions.
Q4. Are there any dietary restrictions while taking Letroz?
A: No specific dietary restrictions are required, but a calcium- and vitamin D-rich diet is often recommended to maintain bone health during therapy.
Q5. Can premenopausal women take Letrozole?
A: Letrozole is generally intended for postmenopausal women. It is not typically recommended for premenopausal breast cancer patients, except in specific fertility-related situations under expert supervision.
References
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Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
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Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
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Letrozole [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2020. [Accessed 08 Jul. 2023]. (online) Available from:
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