

Merrobe 500mg Injection
₹632.00 Original price was: ₹632.00.₹275.00Current price is: ₹275.00.
 Prescription Required
Salt : Meropenem (1gm)
Manufacturer : Glenmark Pharmaceuticals Ltd
Packing : 1Â Injection in 1 vial
1. Product Introduction
Merrobe 500mg Injection is a broad-spectrum, prescription antibiotic that contains Meropenem (1gm) as its active ingredient. It belongs to the carbapenem class of antibiotics, which are known for their strong antibacterial activity against a wide variety of bacteria, including both Gram-positive and Gram-negative strains.
This medicine is used to treat serious bacterial infections in various parts of the body such as the lungs, urinary tract, skin, abdomen, and brain (meningitis). It works by stopping the growth of bacteria and destroying their cell walls, thereby clearing the infection.
Merrobe is administered intravenously (IV) under medical supervision, making it suitable for hospital settings where severe infections require quick and effective treatment.
2. Uses of Merrobe 500mg Injection
Merrobe 500mg Injection is widely used in the treatment of several serious bacterial infections, including:
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Lower Respiratory Tract Infections (such as pneumonia and bronchitis)
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Urinary Tract Infections (including complicated cases)
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Intra-abdominal Infections (e.g., peritonitis, abscesses)
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Skin and Soft Tissue Infections
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Gynecological Infections (like pelvic inflammatory disease)
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Bacterial Meningitis (inflammation of the brain lining caused by bacteria)
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Septicemia (Blood Poisoning)
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Febrile Neutropenia (fever with low white blood cells in cancer patients)
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Post-surgical Infections
It is often reserved for infections caused by multi-drug resistant organisms, especially when other antibiotics have failed.
3. Benefits of Merrobe 500mg Injection
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Broad-Spectrum Activity: Merrobe fights a wide range of bacterial pathogens, including strains resistant to other antibiotics.
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Fast-Acting Relief: As an injectable formulation, it works quickly to control serious and life-threatening infections.
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Effective Against Resistant Bacteria: It is often used as a last-resort antibiotic in critically ill patients with infections caused by extended-spectrum beta-lactamase (ESBL) producing bacteria.
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Reduced Risk of Resistance: When used correctly, Meropenem minimizes the chances of bacterial resistance development compared to other classes of antibiotics.
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Safe for Various Age Groups: It can be used in adults, elderly patients, and even in children for conditions like meningitis.
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Hospital-Based Supervision: The IV route ensures proper dosage control, monitoring, and patient safety, especially in intensive care units.
4. Side Effects of Merrobe 500mg Injection
Like all medications, Merrobe 500mg Injection may cause side effects in some individuals. Most are mild and manageable, but a few can be serious.
Common Side Effects:
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Nausea and vomiting
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Diarrhea
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Headache
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Skin rash or redness at the injection site
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Constipation
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Anemia or mild changes in blood cell counts
Serious Side Effects (Seek Immediate Medical Attention):
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Allergic reactions such as rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, and trouble breathing
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Seizures (rare but possible, especially in patients with kidney problems or CNS disorders)
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Clostridium difficile-associated diarrhea (due to disruption of gut bacteria)
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Liver enzyme elevations or hepatitis symptoms (rare)
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Blood disorders like thrombocytopenia or leukopenia in long-term use
Precautions:
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Kidney Function Monitoring: Dose adjustments may be needed in patients with kidney problems.
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Avoid in Allergy to Beta-lactam Antibiotics: Those allergic to penicillins or cephalosporins may also react to Meropenem.
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Avoid Alcohol: Although no direct interaction, alcohol should be avoided during serious infection treatment.
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Pregnancy and Breastfeeding: Should be used only if clearly needed and under medical advice.
5. Frequently Asked Questions (FAQs)
Q1. What is Merrobe 500mg Injection used for?
A1. Merrobe 500mg Injection is used to treat serious bacterial infections like pneumonia, meningitis, abdominal infections, skin infections, urinary tract infections, and infections that occur after surgery or in hospitalized patients.
Q2. How is Merrobe administered?
A2. It is given as an intravenous (IV) injection or infusion in a hospital or clinical setting by a healthcare professional. The dosage and duration depend on the severity of the infection and the patient’s condition.
Q3. Is Merrobe safe during pregnancy?
A3. Meropenem should only be used during pregnancy if prescribed by a doctor. It is generally avoided unless the benefit clearly outweighs the risk.
Q4. Can children take Merrobe 500mg Injection?
A4. Yes, under strict medical supervision, it is used in children, particularly for treating meningitis or other serious infections.
Q5. How long does Merrobe take to show improvement?
A5. Some improvement is usually seen within 24–48 hours of starting treatment. However, the full course must be completed as prescribed to avoid recurrence or resistance.
References
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Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1500.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 866-67.
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CiplaMed. Meropenem [Prescribing Information]. 03 Jun. 2021. [Accessed 11 Jul. 2023]. (online) Available from:
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