Nitib 140mg Capsule

1. Product Introduction

Nitib 140mg Capsule is a prescription anti-cancer medicine that contains Ibrutinib, a targeted therapy classified as a Bruton’s Tyrosine Kinase (BTK) inhibitor. It is primarily used in the treatment of various blood cancers, especially those involving B-cells such as chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), and Waldenström’s macroglobulinemia (WM).

Ibrutinib works by blocking BTK, an enzyme that plays a critical role in the survival and proliferation of cancerous B-cells. By inhibiting this pathway, Nitib disrupts the growth of cancer cells and induces programmed cell death (apoptosis), effectively helping manage and slow down disease progression.

This medicine is typically taken orally once a day, and the dose may vary depending on the condition being treated. It is a long-term therapy and must be taken regularly as prescribed by a qualified oncologist.

2. Uses of This Medicine

Nitib 140mg Capsule is used in the treatment of various types of blood-related cancers. Key therapeutic indications include:

• Chronic Lymphocytic Leukemia (CLL):
  CLL is a slow-growing type of leukemia that affects white blood cells. Nitib is effective in managing both untreated and previously treated CLL patients.

• Small Lymphocytic Lymphoma (SLL):
  SLL is similar to CLL and involves the lymph nodes. Nitib helps reduce lymph node swelling and control disease progression.

• Mantle Cell Lymphoma (MCL):
  A rare and aggressive form of non-Hodgkin lymphoma. Nitib is used when patients have failed other treatments.

• Waldenström’s Macroglobulinemia (WM):
  A rare type of non-Hodgkin lymphoma that produces excess IgM antibodies. Nitib helps control abnormal cell production.

• Marginal Zone Lymphoma (MZL):
  In certain cases of relapsed or refractory MZL, Nitib may be used after prior treatments have failed.

• Chronic Graft-versus-Host Disease (cGVHD):
  Nitib is also used in patients who have developed cGVHD after stem cell transplantation and are resistant to corticosteroids.

3. Benefits of This Medicine

Nitib 140mg Capsule offers multiple benefits in managing and treating blood cancers:

• Targeted Therapy
  As a BTK inhibitor, Ibrutinib specifically targets cancer-causing cells, minimizing harm to normal cells compared to traditional chemotherapy.

• Effective in Relapsed or Resistant Cases
  Particularly beneficial in patients who have relapsed or failed to respond to previous cancer treatments.

• Improved Survival Rates
  Clinical studies have shown that Ibrutinib improves progression-free survival and overall survival in patients with CLL and other B-cell malignancies.

• Oral Dosage Form
  Convenient to take at home without the need for hospital-based infusion therapies.

• Symptom Relief
  Helps reduce symptoms like swollen lymph nodes, fatigue, night sweats, and fever associated with blood cancers.

• Slows Disease Progression
  Helps delay the need for further aggressive treatments and improves quality of life.

4. Side Effects

Like all medications, Nitib 140mg Capsule can cause side effects. These may vary in severity and not all patients will experience them.

Common Side Effects:

• Diarrhea

• Nausea

• Fatigue

• Muscle and joint pain

• Cough

• Rash

• Headache

Serious Side Effects (consult your doctor immediately if these occur):

• Bleeding (including serious internal bleeding)

• Irregular heartbeat (Atrial fibrillation)

• High blood pressure (Hypertension)

• Infections (especially respiratory or urinary)

• Low blood cell counts (anemia, neutropenia, thrombocytopenia)

• Liver enzyme elevation

• Secondary cancers (rare)

Note: Regular monitoring with blood tests and periodic check-ups is necessary during the course of treatment.

5. Frequently Asked Questions (FAQ)

Q1. What is Nitib 140mg Capsule used for?
A: Nitib is used to treat various blood cancers such as chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), Waldenström’s macroglobulinemia (WM), and chronic graft-versus-host disease (cGVHD).

Q2. How does Ibrutinib work?
A: Ibrutinib blocks the BTK enzyme, which is essential for the survival of cancerous B-cells. By inhibiting this enzyme, it stops cancer cells from multiplying and causes them to die.

Q3. How should I take Nitib 140mg Capsule?
A: It should be taken once daily with a glass of water at the same time each day. Do not crush or chew the capsule. Take it exactly as prescribed by your doctor.

Q4. Can Nitib be taken with food?
A: It can be taken with or without food, but it’s important to stay consistent in how you take it daily.

Q5. What precautions should I take while using this medicine?
A: Avoid activities that may increase your risk of bleeding or injury. Inform your doctor about any other medications or supplements you are taking. Avoid grapefruit or grapefruit juice as it may increase side effects.