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Pacliall 100mg Injection

  Prescription Required

Salt : Paclitaxel

Manufacturer : MANKIND PHARMACEUTICALS LIMITED

Packing : 1 Vial(s)

Description

1. Product Introduction

Pacliall 100mg Injection is a chemotherapy medication that contains Paclitaxel, a well-known anti-cancer agent used to treat various types of cancers. It belongs to a class of drugs known as taxanes, which work by stopping the growth and spread of cancer cells. Paclitaxel interferes with the normal function of microtubules during cell division, thereby inhibiting the growth of cancer cells and eventually destroying them.

Pacliall 100mg is typically administered as an intravenous (IV) infusion under the supervision of an experienced oncologist or healthcare provider. It is used alone or in combination with other chemotherapy drugs depending on the type and stage of cancer being treated. The drug is known for its potent action and is widely used in modern oncology practices.


2. Uses of This Medicine

Pacliall 100mg Injection is used to treat a variety of cancers, including but not limited to:

  • Ovarian Cancer: Often used as first-line or second-line therapy, either alone or in combination with other drugs.

  • Breast Cancer: Effective in both early-stage and metastatic breast cancer.

  • Non-Small Cell Lung Cancer (NSCLC): Used in combination with platinum-based chemotherapy.

  • Kaposi’s Sarcoma: Especially in patients with AIDS-related Kaposi’s Sarcoma.

  • Pancreatic Cancer: Often used in combination with gemcitabine.

  • Head and Neck Cancer: In advanced stages or when other treatments have failed.

This medication is administered in a controlled clinical environment due to its potent nature and the need for close monitoring during and after infusion.


3. Benefits of This Medicine

Pacliall 100mg Injection offers multiple therapeutic benefits in the treatment of cancer:

  • Effective Tumor Reduction: Helps shrink the size of tumors and reduce cancer cell proliferation.

  • Improves Survival: Extends overall survival rates in many cancers when used in the appropriate combination and regimen.

  • Versatile Treatment Option: Used to treat a wide range of cancers in different stages, either alone or with other drugs.

  • Proven Efficacy: Backed by years of clinical research and approved by leading oncology guidelines worldwide.

  • Useful in Drug-Resistant Cancers: Especially valuable when cancer has not responded to other chemotherapy options.

  • Well-Studied Drug: With a well-documented safety and efficacy profile, making it a trusted choice in cancer management.


4. Side Effects

Like all chemotherapy medications, Pacliall 100mg Injection may cause some side effects. These vary from person to person and can range from mild to severe. It is important that patients are monitored closely during treatment.

Common Side Effects:

  • Nausea and vomiting

  • Hair loss (alopecia)

  • Fatigue or weakness

  • Loss of appetite

  • Diarrhea or constipation

  • Muscle or joint pain

  • Low blood counts (anemia, neutropenia, thrombocytopenia)

Serious Side Effects (require immediate medical attention):

  • Allergic reactions (rash, difficulty breathing, facial swelling)

  • Heart rhythm changes

  • Peripheral neuropathy (numbness, tingling, or pain in hands/feet)

  • Severe infections due to low white blood cells

  • Liver function changes

  • Mouth sores

To minimize side effects, premedications like steroids and antihistamines are often given before administering Pacliall to reduce the risk of hypersensitivity reactions.


5. Frequently Asked Questions (FAQ)

Q1. What is Pacliall 100mg Injection used for?
It is used for the treatment of several types of cancer, including breast, ovarian, lung, pancreatic, and Kaposi’s sarcoma. It helps to stop the growth and spread of cancer cells.

Q2. How is this injection administered?
Pacliall is given as an intravenous (IV) infusion, usually over a period of 1 to 3 hours, depending on the dosage and combination with other drugs. It must be administered in a hospital or clinical setting under medical supervision.

Q3. Can Pacliall cause hair loss?
Yes, hair loss is a common side effect. However, it is temporary, and hair usually regrows after the completion of treatment.

Q4. Are there any precautions before taking this injection?
Yes, inform your doctor if you have liver disease, heart issues, or any history of allergic reactions to similar chemotherapy drugs. Premedication may be required to prevent allergic reactions.

Q5. Can pregnant or breastfeeding women use this medicine?
No, Pacliall is not safe during pregnancy or breastfeeding as it can harm the baby. Effective contraception should be used during and for some time after treatment.


References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1707 – 1709.
  2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
  3. Hospira UK Limited, Electronic medicines compendium (emc), [ Revised on March 2020] [ Accessed on 22nd June 2021], https://www.medicines.org.uk/emc/files/pil.3891.pdf
  4. Bristol-Myers Squibb Company, US Food and Drug Administration, [ Revised on April 2011] [ Accessed on 22nd June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/lab el/2011/020262s049lbl.pdf

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Shipping & Delivery

Shipping Policy

We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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