Pazinib 400mg Tablet

1. Product Introduction

Pazinib 400mg Tablet is a prescription medication that contains Pazopanib (400mg) as its active ingredient. Pazopanib is a targeted therapy drug, primarily used in the treatment of certain types of cancers such as kidney cancer (advanced renal cell carcinoma) and soft tissue sarcoma. It belongs to a class of medications known as tyrosine kinase inhibitors (TKIs), which work by blocking the action of enzymes that contribute to the growth and spread of cancer cells.

This oral tablet is a part of modern cancer treatments that aim to interfere with specific molecules involved in the progression of cancer, rather than broadly killing all rapidly dividing cells like traditional chemotherapy. Pazinib is often used when other treatment options are not effective or in patients who are not suitable candidates for surgical intervention.

Pazinib should always be taken under the supervision of an oncologist or healthcare provider experienced in cancer therapy. Regular monitoring through blood tests and imaging may be required to evaluate the effectiveness and manage potential side effects of the treatment.

2. Uses of This Medicine

Pazinib 400mg Tablet is primarily used for the following conditions:

• Advanced Renal Cell Carcinoma (RCC):
  It is prescribed to patients with kidney cancer that has spread beyond the kidney or cannot be removed with surgery. Pazopanib helps to slow down or stop the growth of the tumor.

• Soft Tissue Sarcoma (STS):
  Pazinib is also approved for the treatment of certain soft tissue sarcomas, a group of rare cancers that develop in the soft tissues like muscles, fat, and blood vessels, especially when the disease is advanced and unresponsive to chemotherapy.

• Off-label Uses (as advised by a doctor):
  In some cases, it may be used for other cancers or investigational treatments under strict medical supervision.

3. Benefits of This Medicine

• Targeted Therapy:
  Unlike conventional chemotherapy that affects both healthy and cancerous cells, Pazinib selectively targets cancer cells, making the treatment more efficient and often better tolerated.

• Slows Tumor Progression:
  Pazinib helps in delaying the progression of cancer by inhibiting the formation of new blood vessels (angiogenesis) that tumors need for growth and survival.

• Oral Administration:
  As an oral tablet, Pazinib offers convenience for patients, eliminating the need for hospital-based intravenous infusions.

• Improved Quality of Life:
  By controlling tumor growth, reducing cancer-related symptoms, and delaying disease progression, Pazinib contributes to an improved quality of life in cancer patients.

• Effective Second-line Therapy:
  It can be used when other first-line therapies have failed or are not suitable, providing an important alternative in cancer treatment.

4. Side Effects

While Pazinib 400mg Tablet is an effective medication, it may cause certain side effects. Not everyone experiences them, and many are manageable with medical supervision.

Common Side Effects:

• Diarrhea

• Nausea or vomiting

• High blood pressure (hypertension)

• Loss of appetite

• Fatigue or weakness

• Hair color changes

• Weight loss

• Changes in liver function tests (elevated liver enzymes)

Serious Side Effects (require immediate medical attention):

• Liver toxicity (jaundice, dark urine, severe abdominal pain)

• Heart problems (irregular heartbeat, chest pain)

• Blood clots

• Bleeding issues

• Protein in the urine

• Wound healing complications

Precautions:

• Liver function tests should be monitored regularly.

• Avoid grapefruit or grapefruit juice while taking this medicine.

• Use effective contraception during and for a period after the treatment.

• Inform your doctor of any existing heart, liver, or kidney conditions.

Always consult your doctor if you experience any unusual or severe symptoms while taking this medication.

5. Frequently Asked Questions (FAQs)

Q1. How should I take Pazinib 400mg Tablet?
A: Pazinib should be taken on an empty stomach, at least one hour before or two hours after food. Swallow the tablet whole with water—do not crush or chew it.

Q2. How long will I need to take this medication?
A: The duration of treatment depends on your response, tolerance to side effects, and progression of the disease. Your doctor will guide the treatment timeline based on periodic assessments.

Q3. Can I take other medicines along with Pazinib?
A: Some medicines can interact with Pazinib and affect its efficacy or increase side effects. Inform your doctor about all medicines, supplements, or herbal products you are taking.

Q4. What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose—do not double up.

Q5. Can pregnant or breastfeeding women take Pazinib?
A: No, Pazinib is not recommended during pregnancy or breastfeeding due to potential harm to the baby. Effective birth control is advised during and after treatment as recommended by your doctor.