Sorafenat 200mg Tablet 120’s

1. Product Introduction

Sorafenat 200mg Tablet is a targeted anti-cancer medication that contains Sorafenib, a kinase inhibitor used in the treatment of certain types of cancer. It is primarily used in patients with liver cancer (hepatocellular carcinoma), kidney cancer (renal cell carcinoma), and thyroid cancer (differentiated thyroid carcinoma) that cannot be treated with surgery or has spread to other parts of the body.

Sorafenib works by blocking abnormal proteins that signal cancer cells to grow. It interferes with the growth and spread of cancer cells, while also cutting off blood supply to tumors by inhibiting certain enzymes involved in tumor angiogenesis (blood vessel growth). As an oral medication, Sorafenat 200mg offers convenience and is usually taken twice daily.

2. Uses of Sorafenat 200mg Tablet

Sorafenat is prescribed by oncologists for the treatment of:

• Hepatocellular Carcinoma (HCC):
  It is the most common form of primary liver cancer, often occurring in patients with chronic liver disease or cirrhosis.

• Advanced Renal Cell Carcinoma (RCC):
  Sorafenib is effective in treating kidney cancer that has spread beyond the kidney and cannot be surgically removed.

• Differentiated Thyroid Carcinoma (DTC):
  Used in patients with radioactive iodine-refractory thyroid cancer, where traditional treatments are ineffective.

Note: Sorafenat is not a cure for cancer but helps to control the disease progression and improve survival rates.

3. Benefits of Sorafenat 200mg Tablet

• Targeted Therapy:
  Sorafenib specifically inhibits multiple cancer-causing kinases, making it more selective than traditional chemotherapy and reducing damage to healthy cells.

• Slows Tumor Growth:
  It works to inhibit tumor cell proliferation and angiogenesis, effectively slowing down the spread of cancer.

• Improves Progression-Free Survival:
  Clinical trials have shown that Sorafenib increases the duration patients live without disease progression, especially in liver and kidney cancers.

• Convenient Oral Administration:
  Being an oral tablet, it allows patients to take the medication at home without the need for hospital visits for infusions.

• Well-Studied and Widely Used:
  Sorafenib is one of the most widely studied kinase inhibitors, approved by regulatory authorities such as the FDA and used globally.

4. Side Effects

Like all anti-cancer medications, Sorafenat 200mg may cause side effects. While not everyone experiences them, some common and serious adverse reactions include:

Common Side Effects:

• Fatigue or weakness

• Loss of appetite

• Diarrhea

• Weight loss

• Hair thinning or loss

• Rash, dry skin, or hand-foot skin reaction (redness, pain, or swelling on palms and soles)

• Nausea or vomiting

• Abdominal pain

Serious Side Effects:

• High blood pressure

• Bleeding problems

• Heart issues (chest pain, heart attack symptoms)

• Liver dysfunction (elevated liver enzymes)

• Impaired wound healing

• Low white blood cell or platelet counts

Precautions:

• Regular blood tests are essential to monitor liver function, kidney function, and complete blood counts.

• Avoid grapefruit juice and certain medications that may interfere with Sorafenib metabolism.

• Patients should inform their doctor if they are undergoing surgery, as Sorafenib may affect healing.

5. Frequently Asked Questions (FAQ)

Q1. How does Sorafenat 200mg Tablet work?
Sorafenib inhibits specific enzymes (tyrosine kinases) involved in tumor growth and blood supply. It blocks signals that promote cancer cell proliferation and angiogenesis.

Q2. How should I take Sorafenat?
Sorafenat should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal. The usual dose is 400mg daily (200mg twice a day), but your doctor may adjust it based on tolerance and response.

Q3. Can I stop taking Sorafenat if I feel better?
No. You should not stop taking Sorafenat unless advised by your doctor. Stopping abruptly can lead to rapid disease progression.

Q4. What happens if I miss a dose?
If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed one and continue your regular schedule. Do not double the dose.

Q5. How long do I need to take Sorafenat?
The duration depends on your response to treatment and tolerability. It can range from a few months to long-term use under regular supervision.