Temorel 100mg Capsule

1. Product Introduction

Temorel 100mg Capsule contains Temozolomide, an oral chemotherapy drug used in the treatment of certain types of brain tumors. It belongs to a class of anti-cancer medications known as alkylating agents that work by interfering with the DNA of cancer cells, preventing them from multiplying and eventually destroying them.

Temozolomide is particularly effective against glioblastoma multiforme and anaplastic astrocytoma, two aggressive types of brain cancer. Temorel 100mg is available in capsule form, allowing for convenient at-home treatment under the supervision of an oncologist.

This medicine is typically prescribed either alone or alongside radiation therapy and may also be used as part of a maintenance therapy plan following initial treatment.

2. Uses of This Medicine

Temorel 100mg Capsule is primarily used for the treatment of:

• Glioblastoma Multiforme (GBM): A fast-growing and highly malignant type of brain tumor. Temozolomide is used in combination with radiotherapy during the initial phase and then as maintenance therapy afterward.

• Anaplastic Astrocytoma: A rare and aggressive type of brain tumor for which Temozolomide is used, especially when other treatments are ineffective or as a second-line option.

It may also be used off-label for other malignancies based on the oncologist’s judgment.

3. Benefits of This Medicine

• Improves Survival in Brain Tumor Patients: Temozolomide has been clinically proven to extend survival and slow tumor progression in patients with glioblastoma and anaplastic astrocytoma.

• Oral Chemotherapy Option: Unlike traditional chemotherapy that requires hospital visits and intravenous infusions, Temorel 100mg offers the convenience of oral administration at home.

• Used Alongside Radiotherapy: Temozolomide enhances the effectiveness of radiation therapy, helping achieve better outcomes during the initial treatment phase.

• Better Tolerability: It has a more favorable side effect profile compared to many other chemotherapy agents, making it a preferred choice for long-term use.

• Maintenance Therapy: Temozolomide is also used for long-term maintenance after radiotherapy to help prevent recurrence.

4. Side Effects

While Temorel 100mg Capsule is effective in treating certain cancers, like all chemotherapy medicines, it may cause side effects. These may range from mild to severe and must be reported to a doctor for timely management.

Common Side Effects:

• Nausea and vomiting

• Fatigue

• Loss of appetite

• Constipation or diarrhea

• Headache

• Hair thinning or hair loss

• Rash or skin irritation

Serious Side Effects:

• Low Blood Cell Counts (neutropenia, thrombocytopenia, anemia): This can increase the risk of infection, bleeding, and fatigue.

• Increased Liver Enzymes: Regular liver function tests are needed.

• Infections: Due to reduced white blood cells.

• Seizures or Neurological Changes: Especially in patients with brain tumors.

• Allergic Reactions: Symptoms such as swelling, difficulty breathing, or rash may occur.

Precautions:

• Frequent blood tests to monitor liver function and blood counts are essential.

• Not recommended for pregnant or breastfeeding women.

• Use effective contraception during treatment and for at least 6 months afterward.

• Avoid contact with sick individuals to minimize the risk of infection.

5. Frequently Asked Questions (FAQ)

Q1. What is Temorel 100mg Capsule used for?
A: It is used to treat aggressive brain cancers such as glioblastoma multiforme and anaplastic astrocytoma, either alone or in combination with radiation therapy.

Q2. How does Temozolomide work?
A: Temozolomide is an alkylating agent that damages the DNA in cancer cells, preventing their growth and causing them to die.

Q3. How should I take Temorel 100mg?
A: Take the capsule on an empty stomach, usually once daily, as prescribed by your oncologist. Do not crush or chew the capsule. Swallow it whole with water.

Q4. Can I stop taking the medicine if I feel better?
A: No, do not stop or change the dose without your doctor’s guidance. Even if you feel better, completing the full treatment cycle is crucial for its effectiveness.

Q5. Are there any food or drug interactions I should be aware of?
A: Take Temozolomide on an empty stomach. Inform your doctor about all other medications, supplements, or herbal products you are using to avoid potential interactions.