Trombonat 25mg Tablet

1. Product Introduction

Trombonat 25mg Tablet is a prescription medicine that contains Eltrombopag as its active ingredient. It is primarily used to treat low platelet counts in specific blood-related disorders, including chronic immune thrombocytopenia (ITP), thrombocytopenia associated with hepatitis C, and severe aplastic anemia. Belonging to the class of thrombopoietin receptor agonists, Trombonat works by stimulating the bone marrow to produce more platelets—cells essential for blood clotting and the prevention of bleeding.

This medicine is an oral therapy that provides an alternative to more invasive treatments like platelet transfusions or immunoglobulin therapy. Trombonat is especially beneficial for patients who have not responded adequately to conventional treatments like corticosteroids or splenectomy. By effectively improving platelet levels, it helps reduce the frequency and severity of bleeding episodes, allowing patients to lead a safer and more manageable life.

2. Uses of Trombonat 25mg Tablet

Trombonat 25mg Tablet is used in the treatment of the following conditions:

• Chronic Immune Thrombocytopenia (ITP): For adults and children who have had an inadequate response to first-line treatments like steroids, immunoglobulins, or surgery (splenectomy). It helps increase platelet counts and reduce bleeding risks.

• Thrombocytopenia in Chronic Hepatitis C: In patients with chronic hepatitis C infection to manage low platelet counts, especially when undergoing interferon-based therapy.

• Severe Aplastic Anemia (SAA): In adult patients with severe aplastic anemia who have not responded sufficiently to immunosuppressive therapy.

Trombonat does not cure these conditions but plays a critical role in managing platelet levels to prevent bleeding-related complications.

3. Benefits of Trombonat 25mg Tablet

• Improves Platelet Count: Trombonat effectively boosts platelet production in the bone marrow, helping prevent spontaneous bleeding and bruising, especially in patients with severely low counts.

• Reduces Need for Transfusions: By maintaining healthier platelet levels, it reduces the need for platelet transfusions in certain patients, particularly those undergoing antiviral therapy or with bone marrow disorders.

• Supports Interferon Therapy: In hepatitis C patients, Trombonat helps maintain platelet counts during interferon-based treatments, allowing uninterrupted antiviral therapy.

• Oral Convenience: Unlike injectable treatments, Trombonat comes in tablet form, making it easier and more comfortable for long-term use.

• Alternative to Invasive Procedures: Especially in patients not responding to splenectomy or other immune-modulating treatments, Trombonat provides an effective oral alternative.

• Improved Quality of Life: By reducing the risks associated with low platelets—such as nosebleeds, gum bleeding, and internal hemorrhages—it offers patients a safer, more stable daily routine.

4. Side Effects

Like all medications, Trombonat 25mg Tablet may cause some side effects. Most side effects are mild and temporary, but some may require medical attention.

Common Side Effects:

• Headache

• Nausea

• Diarrhea

• Fatigue or weakness

• Muscle aches

• Upper respiratory infections

Serious Side Effects (Seek Immediate Help):

• Liver toxicity: Symptoms may include yellowing of the skin/eyes, dark urine, and abdominal pain.

• Blood clots: Especially in patients whose platelet counts increase too much.

• Cataracts: Eye issues, such as blurred vision or difficulty seeing.

• Bone marrow fibrosis: Long-term use may cause scarring in the bone marrow.

• Severe allergic reactions: Including rash, itching/swelling (especially of the face/tongue), dizziness, or trouble breathing.

Regular blood tests are required during treatment to monitor liver function, platelet counts, and ensure safe dosing.

5. Frequently Asked Questions (FAQ)

Q1. What is Trombonat 25mg Tablet used for?
Trombonat is used to treat low platelet counts in conditions like chronic ITP, hepatitis C-related thrombocytopenia, and severe aplastic anemia. It helps reduce bleeding risks by increasing platelet production.

Q2. How does Eltrombopag in Trombonat work?
Eltrombopag stimulates the thrombopoietin receptor in the bone marrow, which encourages the production of new platelets, essential for normal blood clotting.

Q3. How should I take this medicine?
Trombonat should be taken exactly as prescribed by your doctor. It is usually taken on an empty stomach, either 1 hour before or 2 hours after meals, especially avoiding foods high in calcium, like dairy products, around the time of dosing.

Q4. What happens if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the next scheduled dose, skip the missed one. Do not take a double dose to make up for it.

Q5. Can I take this medicine with other drugs or supplements?
Inform your doctor about all medications and supplements you’re taking. Avoid calcium supplements or antacids close to the time of Trombonat, as they can interfere with absorption.