Trombonat 50mg Tablet

1. Product Introduction

Trombonat 50mg Tablet contains Eltrombopag as its active ingredient and is classified as a thrombopoietin receptor agonist. It is primarily prescribed to help increase the number of platelets in the blood, especially in patients with conditions that cause low platelet counts. Eltrombopag works by stimulating the bone marrow (the soft tissue inside bones) to produce more platelets, which are crucial for blood clotting and preventing excessive bleeding.

Trombonat is widely used in the treatment of chronic immune thrombocytopenia (ITP), hepatitis C-associated thrombocytopenia, and severe aplastic anemia. It offers an oral alternative to more invasive treatments like platelet transfusions, making it a convenient and effective choice for managing blood disorders. Trombonat must be used under medical supervision, with regular monitoring of platelet counts to ensure optimal results and safety.

2. Uses of Trombonat 50mg Tablet

• Chronic Immune Thrombocytopenia (ITP):
  Trombonat is used in adults and children with chronic ITP, particularly when other treatments like corticosteroids, immunoglobulins, or surgical removal of the spleen (splenectomy) have not worked effectively.

• Thrombocytopenia in Hepatitis C Patients:
  It helps treat low platelet counts in patients with chronic hepatitis C infection to allow them to continue antiviral therapy without bleeding complications.

• Severe Aplastic Anemia:
  In patients with severe aplastic anemia who do not respond adequately to immunosuppressive therapy, Trombonat can help stimulate blood cell production, including platelets, red cells, and white cells.

Note:
Trombonat is not a cure for these conditions but is used to manage and improve symptoms by increasing platelet counts.

3. Benefits of Trombonat 50mg Tablet

• Improves Platelet Levels:
  Trombonat directly stimulates platelet production, helping reduce the risk of serious bleeding events.

• Reduces the Need for Blood Transfusions:
  By maintaining platelet counts, it lowers the dependency on platelet transfusions, minimizing the risks associated with transfusion reactions.

• Oral Administration:
  As a tablet, Trombonat offers a convenient, non-invasive option compared to injections or transfusions.

• Facilitates Antiviral Therapy:
  In hepatitis C patients, it helps maintain platelet levels to allow uninterrupted antiviral treatments, improving overall disease management.

• Potential for Multi-Lineage Blood Cell Growth:
  In severe aplastic anemia, besides platelets, it may stimulate other blood cells, offering broader hematologic improvement.

• Customized Dosing:
  Dosage can be adjusted based on the individual response, providing personalized care for optimal effectiveness.

4. Side Effects

Like all medications, Trombonat 50mg Tablet may cause side effects, though not everyone experiences them. Close medical supervision helps manage these effectively.

• Common Side Effects:

  • Nausea

  • Diarrhea

  • Fatigue

  • Headache

  • Muscle pain

  • Loss of appetite

• Serious Side Effects:

  • Liver problems (elevated liver enzymes, jaundice)

  • Blood clots (deep vein thrombosis, pulmonary embolism)

  • Cataracts

  • Bone marrow fibrosis (scarring in the bone marrow)

• Rare Side Effects:

  • Difficulty breathing

  • Vision changes

  • Severe allergic reactions (rash, itching, swelling)

Precautions:
Routine blood tests, liver function tests, and eye examinations are recommended during treatment to monitor for potential complications.

Important:
Do not stop or change the dose without consulting your doctor, even if you feel well, as abrupt changes can lead to serious complications.

5. Frequently Asked Questions (FAQ)

Q1. How does Trombonat 50mg Tablet work?
A1. Trombonat works by stimulating the thrombopoietin receptors in the bone marrow, leading to an increased production of platelets, which are vital for blood clotting.

Q2. How should Trombonat 50mg Tablet be taken?
A2. Trombonat should be taken exactly as prescribed by your doctor, usually on an empty stomach (at least 1 hour before or 2 hours after meals), and should not be taken with dairy products, antacids, or supplements containing calcium, iron, or magnesium.

Q3. How long does it take for Trombonat to show results?
A3. Some patients may notice an improvement in platelet counts within 1–2 weeks, but it may take longer depending on individual response and condition severity.

Q4. Can I stop taking Trombonat once my platelet counts improve?
A4. No. Discontinuing the medication without your doctor’s advice can cause platelet levels to drop again, increasing the risk of bleeding.

Q5. What happens if I miss a dose of Trombonat?
A5. If you miss a dose, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.