

Voritrop 200mg Tablet
₹4,960.00 Original price was: ₹4,960.00.₹3,500.00Current price is: ₹3,500.00.
 Prescription Required
Salt : Voriconazole
Manufacturer : Intas Pharmaceuticals Ltd
Packing : 4Â tablets in 1 strip
1. Product Introduction
Voritrop 200mg Tablet is an advanced antifungal medication that contains Voriconazole, a potent triazole compound. It is primarily used to treat serious, invasive fungal infections that can be life-threatening, especially in patients with weakened immune systems. Voriconazole works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane. This disruption weakens the structure of the fungal cell, causing it to die and preventing the infection from spreading further.
Voritrop is a prescription-only medication and should be used under the supervision of a healthcare professional. It is available in tablet form and is usually taken orally. The drug is known for its broad-spectrum antifungal activity, particularly effective against Aspergillus and Candida species, including strains resistant to other antifungal drugs.
2. Uses of This Medicine
Voritrop 200mg Tablet is used to treat several serious fungal infections, especially in immunocompromised patients such as those undergoing chemotherapy, organ transplantation, or with HIV/AIDS. The main indications include:
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Invasive Aspergillosis
A life-threatening infection caused by Aspergillus species, often affecting the lungs. -
Candidemia and Disseminated Candida Infections
Bloodstream and systemic infections caused by Candida species, especially in hospitalized or ICU patients. -
Esophageal and Oropharyngeal Candidiasis
Fungal infections in the throat and mouth, particularly in individuals with a weakened immune system. -
Fungal Infections Resistant to Other Antifungals
Used when other treatments such as fluconazole or amphotericin B have failed or are not suitable. -
Empiric Treatment in Febrile Neutropenia
Given as a preventive measure in patients with unexplained fever and low white blood cell count who are at risk of fungal infections.
3. Benefits of This Medicine
Voritrop 200mg Tablet offers significant clinical benefits, especially in managing complex and dangerous fungal infections:
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Broad Antifungal Spectrum
Effective against both common and rare fungal pathogens, including Aspergillus, Candida, Scedosporium, and Fusarium species. -
Oral Administration
Offers a convenient oral route for long-term therapy without requiring hospitalization or IV access. -
Resistance Management
Works well in infections resistant to standard antifungal agents, offering a solution for difficult-to-treat cases. -
High Penetration
Excellent tissue penetration, including into the brain and eyes, making it useful for fungal infections in these sensitive areas. -
Reduced Mortality
Proven to reduce the risk of death in patients with invasive fungal infections, especially when started early. -
Well-Tolerated Alternative
Compared to older antifungals like amphotericin B, Voriconazole has a better safety profile and fewer nephrotoxic effects.
4. Side Effects
Like all medications, Voritrop 200mg Tablet may cause side effects. Most are mild and temporary, but some may require medical attention.
Common Side Effects:
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Visual disturbances (blurred vision, altered color perception)
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Fever
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Headache
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Nausea or vomiting
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Diarrhea
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Rash
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Liver enzyme elevation
Less Common But Serious Side Effects:
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Hepatitis or liver toxicity
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Photosensitivity and skin reactions (especially with long-term use)
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Hallucinations or confusion
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Arrhythmia (irregular heartbeats)
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Severe allergic reactions (rash, swelling, difficulty breathing)
Note: Regular liver function tests and eye examinations may be recommended during treatment. Inform your doctor immediately if you notice yellowing of the skin or eyes, persistent fatigue, or visual problems.
5. Frequently Asked Questions (FAQ)
Q1. What is Voritrop 200mg Tablet used for?
Voritrop is used to treat serious fungal infections like invasive aspergillosis, candidemia, and infections resistant to other antifungals.
Q2. How should I take Voritrop?
Take Voritrop exactly as prescribed by your doctor. It should be taken on an empty stomach, preferably 1 hour before or after meals, for better absorption.
Q3. Can I stop taking Voritrop once I feel better?
No, do not stop taking the medicine without your doctor’s approval. Incomplete treatment may cause the infection to return or become resistant.
Q4. What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose.
Q5. Can Voritrop be taken with other medications?
Voritrop may interact with several medications, including certain antibiotics, antivirals, and anticoagulants. Always inform your doctor about all other medicines you’re taking.
References
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Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1580-81.
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Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1498-99.
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CiplaMed. Voriconazole [Prescribing Information]. [Last Updated: Oct. 2013] [Accessed 07 Aug. 2023]. (online) Available from:Â
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